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Two brain models against the blurry background of Prof. Inglese and two of her colleagues looking at a computer screen together.
Neurology

Pushing the boundaries in multiple sclerosis research

Clinicians and researchers are pioneers whose insights help us better understand and diagnose challenging diseases like cancer, neurodegenerative diseases, and complex musculoskeletal conditions.

4min
Doris Pischitz
Published on September 18, 2023

Professor Matilde Inglese, MD, PhD, is one such pioneer. 

A lifelong disease

Portrait photo of Professor Inglese sitting at the professor's desk in the lecture hall.

MS is a multifactorial condition where both genetic and environmental factors could increase the risk of developing the disease.

Professor Matilde Inglese, MD, PhD, Professor of Neurology, University of Genoa, Italy, head of the Multiple Sclerosis (MS) Center, IRCCS Ospedale Policlinico San Martino

The role of magnetic resonance imaging

“Today, MRI helps us find a correct diagnosis and select the right treatments, which can improve symptoms,” says Inglese.

Monitoring progression and treatment response

MRI image of MS lesions in the brain
MS lesions manifest as hyperintense (i.e. bright) spots in the white matter if imaged using FLAIR (Fluid Attenuated Inversion Recovery). The lesions here are on the right side.

Overcoming current limitations

MRI image of MS lesions in the brain
In contrast to FLAIR, this MPRAGE (Magnetization Prepared Rapid Acquisition with Gradient Echoes) image displays MS lesions as dark spots in the white matter. Again, the spots are on the right side.

Hope on the horizon

Prof. Inglese walking down the corridor of the research building, looking at her mobile phone.
Shaping healthcare in 2023 and beyond
Key visual for Siemens Healthineers Shape 23 Keynote

November 14, 2022

Siemens Healthineers Shape 23 Keynote

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Join us and hear some of the world’s most respected healthcare leaders share insights into how to address the challenges posed by cancer, how high-quality care can be brought to more patients, and how to address the workforce crisis.
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By Doris Pischitz
Doris Pischitz is an editor in corporate communications at Siemens Healthineers. The team specializes in topics related to healthcare, medical technology, disease areas, and digitalization.

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Innovation culture

What if we could overcome limitations in MRI?

Neurology

Multiple sclerosis: Improve monitoring, inform treatment decisions

  1. [1] Rising prevalence of multiple sclerosis worldwide: Insights from the Atlas of MS, third edition - PMC (nih.gov)

    [2] Disease-modifying Therapies for Multiple Sclerosis (multiplesclerosisnewstoday.com)

    [3] Medicines in development. 2021 report: neurodegenerative diseases. Pharmaceutical Research and Manufacturers of America. 12 October 2021

  1. The product is still under development and not commercially available yet. Its future availability cannot be ensured.


    The statements by Siemens Healthineers customers described herein are based on results that were achieved in the customer’s unique setting. Since there is no “typical” hospital and many variables exist (e.g., hospital size, case mix, level of IT adoption) there can be no guarantee that other customers will achieve the same results.